The hedgehog gene family in Drosophila and vertebrate development

The segment polarity gene hedgehog plays a central role in cell patterning during embryonic and post-embryonic development of the dipteran, Drosophila melanogaster. Recent studies have identified a family of hedgehog related genes in vertebrates; one of these, Sonic hedgehog is implicated in positio...

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Bibliographic Details
Published in:	Development (Cambridge) Vol. 1994; no. Supplement; pp. 43 - 51
Main Authors:	Fietz, M J, Concordet, J P, Barbosa, R, Johnson, R, Krauss, S, McMahon, A P, Tabin, C, Ingham, P W
Format:	Journal Article
Language:	English
Published:	England 1994
Subjects:	Amino Acid Sequence Animals Chick Embryo Drosophila - embryology Drosophila - genetics Drosophila - growth & development Drosophila Proteins Embryonic Induction - genetics Extremities - embryology Gene Expression Genes, Insect Hedgehog Proteins Mice Molecular Sequence Data Morphogenesis - genetics Proteins - genetics Sequence Alignment Vertebrates - embryology Vertebrates - genetics Vertebrates - growth & development
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Summary:	The segment polarity gene hedgehog plays a central role in cell patterning during embryonic and post-embryonic development of the dipteran, Drosophila melanogaster. Recent studies have identified a family of hedgehog related genes in vertebrates; one of these, Sonic hedgehog is implicated in positional signalling processes that show interesting similarities with those controlled by its Drosophila homologue.
ISSN:	0950-1991 1477-9129
DOI:	10.1242/dev.1994.Supplement.43