Topical mitomycin therapy in the pediatric airway: State of the art

Topical mitomycin therapy in the pediatric airway: State of the art

Although topical Mitomycin C has been used for more than 20 years, it is a relative newcomer to the field of otolaryngology. This intraoperative therapy is the first of its kind to offer surgeons the ability to modify the healing response at the molecular level. To understand mitomycin's use an...

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Bibliographic Details
Published in:Operative techniques in otolaryngology--head and neck surgery Vol. 13; no. 1; pp. 57 - 64
Main Authors: Cable, Benjamin B., Pazos, George A., Brietzke, Scott E., Mair, Eric A.
Format: Journal Article
Language:English
Published: Elsevier Inc 2002
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Summary:Although topical Mitomycin C has been used for more than 20 years, it is a relative newcomer to the field of otolaryngology. This intraoperative therapy is the first of its kind to offer surgeons the ability to modify the healing response at the molecular level. To understand mitomycin's use and applications, it is important to review both the evolution of this drug in our field and the rapidly changing understanding of its mechanism of action. With this, a representative case series is presented that details its practical use throughout the pediatric airway.
ISSN:1043-1810
1557-9395
DOI:10.1053/otot.2002.29189