Severe cardiac and ophthalmologic malformations in an infant exposed to diphenylhydantoin in utero

A newborn male infant with multiple congenital malformations including lethal cardiac malformations and severe ophthalmic malformations is described. The infant was exposed in utero to hydantoin. There is no other identifiable cause for the malformations apparent in the infant's or his family&#...

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Bibliographic Details
Published in:	Pediatrics (Evanston) Vol. 69; no. 2; pp. 202 - 203
Main Authors:	Bartoshesky, L E, Bhan, I, Nagpaul, K, Pashayan, H
Format:	Journal Article
Language:	English
Published:	United States 01-02-1982
Subjects:	Abnormalities, Drug-Induced - diagnosis Abnormalities, Multiple - chemically induced Adult Eye Diseases - chemically induced Female Heart Defects, Congenital - chemically induced Heart Septal Defects, Atrial - chemically induced Heart Septal Defects, Ventricular - chemically induced Humans Infant, Newborn Infant, Premature, Diseases - chemically induced Male Maternal-Fetal Exchange - drug effects Phenytoin - adverse effects Pregnancy
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Summary:	A newborn male infant with multiple congenital malformations including lethal cardiac malformations and severe ophthalmic malformations is described. The infant was exposed in utero to hydantoin. There is no other identifiable cause for the malformations apparent in the infant's or his family's history.
ISSN:	0031-4005 1098-4275
DOI:	10.1542/peds.69.2.202