The Cell-Migration-Inhibition Correlate of Delayed Hypersensitivity

When nonsensitive cells were incubated with an RNA extract from lymph nodes of human donors sensitive to tuberculin purified-protein-derivative, histoplasmin or both, the migration of these cells from capillary tubes was specifically inhibited by these antigens. This RNA extract contained no detecta...

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Bibliographic Details
Published in:The Journal of immunology (1950) Vol. 101; no. 3; pp. 469 - 480
Main Authors: Thor, Daniel E., Dray, Sheldon
Format: Journal Article
Language:English
Published: 01-09-1968
Online Access:Get full text
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Summary:When nonsensitive cells were incubated with an RNA extract from lymph nodes of human donors sensitive to tuberculin purified-protein-derivative, histoplasmin or both, the migration of these cells from capillary tubes was specifically inhibited by these antigens. This RNA extract contained no detectable DNA and less than 3% protein and was inactivated by RNase but not by DNase or trypsin.
ISSN:0022-1767
1550-6606
DOI:10.4049/jimmunol.101.3.469