Serum progesterone in the management of pregnancy of unknown location: A Singapore experience
The management of pregnancy of unknown location (PUL) currently encompasses multiple blood tests to trend serum beta-human chorionic gonadotropin (hCG) levels every 48 hours and ultrasound scans (USS). This results in multiple hospital visits for patients, causing emotional and economic distress. Th...
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| Published in: | Annals of the Academy of Medicine, Singapore Vol. 53; no. 10; pp. 632 - 634 |
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| Main Authors: | , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
Academy of Medicine Singapore
30-10-2024
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| Online Access: | Get full text |
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| Summary: | The management of pregnancy of unknown location (PUL) currently encompasses multiple blood tests to trend serum beta-human chorionic gonadotropin (hCG) levels every 48 hours and ultrasound scans (USS). This results in multiple hospital visits for patients, causing emotional and economic distress. Therefore, it is important to identify women with PUL at risk of an ectopic pregnancy (EP) requiring close monitoring, and to limit the follow-up for those who are likely to have a viable intrauterine pregnancy (IUP) or a failing pregnancy that may resolve spontaneously. Studies show that a single serum progesterone level can be used for triaging, with centres using cut-offs of 10 nmol/L to 30 nmol/L at which the pregnancy may spontaneously resolve.1-5 |
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| Bibliography: | content type line 23 SourceType-Scholarly Journals-1 ObjectType-Correspondence-1 |
| ISSN: | 0304-4602 2972-4066 0304-4602 2972-4066 |
| DOI: | 10.47102/annals-acadmedsg.2024146 |