Practice Patterns of Cardiovascular Magnetic Resonance Use in the Diagnosis of Pediatric Myocarditis: A Survey-Based Study

• Published in: Journal of cardiovascular magnetic resonance p. 101091
• Main Authors: Jacobs, Hannah M., Soslow, Jonathan H., Cornicelli, Matthew D., Merves, Shae A., Garg, Ruchira, Patel, Mehul D., Agarwal, Arpit, Misra, Nilanjana, DiLorenzo, Michael P., Campbell, M. Jay, Steele, Jeremy, Co-Vu, Jennifer, Robinson, Joshua D., Lee, Simon, Johnson, Jason N.
• Format: Journal Article
• Language: English
• Published: England Elsevier Inc 11-09-2024
• Subjects: Lake Louise Criteria; Myocarditis; Parametric mapping; Pediatric; EGE; LLC; MOLLI; bSSFP; CMR; LGE; COVID-19; Myocarditis; CERAMICi; SARS-CoV-2; SCMR; T; Parametric mapping; T2w; ECV; AHA; EMB; GRE; Lake Louise Criteria; Pediatric; GE
• ISSN: 1097-6647; 1532-429X; 1532-429X
• DOI: 10.1016/j.jocmr.2024.101091

Cardiovascular magnetic resonance (CMR) is used to diagnose myocarditis in adults and children based on the original Lake Louise Criteria (LLC) and more recently the revised LLC. The major change included in the revised LLC was the incorporation of parametric mapping, which significantly increases the sensitivity and specificity of diagnosis. Subsequently, scientific statements have recommended the use of parametric mapping in the diagnosis of myocarditis in children. However, there are some challenges to parametric mapping that are unique to the pediatric population. Our goal is to characterize clinical CMR and parametric mapping practice patterns for diagnosis of myocarditis in pediatric centers.
The Cardiovascular Magnetic Resonance Evaluation in Return to Athletes for Myocarditis in COVID-19 and Immunization Consortium created a REDCap survey to evaluate clinical practice patterns for diagnosis of myocarditis in pediatrics. This survey was distributed to the Society for Cardiovascular Magnetic Resonance community.
59 responses from 51 centers were received, with only one response from each center being utilized. Only 35% of centers (37% of North America, 31% of international) reported using CMR routinely in all patients with a suspicion for myocarditis. Diagnostic uncertainty was noted as the most important reason for CMR, while cost was noted as the least important consideration. The majority of centers reported using the revised LLC (37/51, 72%) compared to original LLC (7/51, 14%) or a hybrid criteria (6/51, 12%). When looking at the use of parametric mapping, only 5/47 (11%) for T1 mapping and 11/49 (22%) for T2 mapping reported having scanner-specific pediatric normative data.
Routine CMR imaging for diagnosis of myocarditis in pediatrics is infrequently performed at surveyed centers despite the focus on a group of non-invasive cardiac imagers. While the majority reported using parametric mapping, few centers reporting having pediatric scanner-specific normative data. This highlights an important gap in the utilization of CMR that may aid in the diagnosis of myocardial disease.
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