Bizarre Parosteal Osteochondromatous Proliferation With Malignant Transformation and Metastases

• Published in: Orthopedics (Thorofare, N.J.) pp. 1 - 5
• Main Authors: Ulrich, Gary, Wood, Robert, Pearson, Jacob, Jiganti, Max, Tedesco, Nicholas
• Format: Journal Article
• Language: English
• Published: United States Slack, Inc 21-10-2024; SLACK INCORPORATED
• Subjects: Adrenal glands; Amputation; Biopsy; Bone cancer; Bone tumors; Calcification; Cartilage; Case reports; Case studies; Complications and side effects; Epidemiology; Histopathology; Joint replacement surgery; Knee; Medical research; Medicine, Experimental; Metastasis; Morphology; Osteoarthritis; Pain; Physiological aspects; Postoperative period; Risk factors; Sarcoma; Tomography; United States
• ISSN: 0147-7447; 1938-2367; 1938-2367
• DOI: 10.3928/01477447-20241016-01

A patient with a benign bizarre parosteal osteochondromatous proliferation (BPOP) located in the anterior knee was treated with resection in preparation for total knee arthroplasty (TKA). The BPOP reoccurred and was treated with re-resection at the time of TKA. The BPOP reoccurred a second time and underwent malignant transformation to a fungating high-grade pleomorphic sarcoma with metastatic lesions. This case highlights the rare potential of a previously benign BPOP to undergo malignant transformation after recurrence. A wide margin resection may be considered primarily when surgery is indicated to prevent recurrence and its potential sequelae. [
. 202x;4x(x):xx-xx.].