Improved production of 68Ga-Pentixafor using cartridge mediated cation exchange purification

Improved production of 68Ga-Pentixafor using cartridge mediated cation exchange purification

•Streamlined automated production of [68Ga]Ga-pentixafor.•Increased [68Ga]Ga-pentixafor yield by application of a Multi Generator Tool.•Reduced synthesis time of 14,5 min.•Significant reduction of ethanol content (3,5 ± 0.5 mg/mL).

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Bibliographic Details
Published in:Applied radiation and isotopes Vol. 189; p. 110447
Main Authors: Nader, M., Herrmann, K., Kunkel, F., Zarrad, F., Pacelli, A., Fendler, W., Koplin, S.
Format: Journal Article
Language:English
Published: Elsevier Ltd 01-11-2022
Online Access:Get full text
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Description
Summary:•Streamlined automated production of [68Ga]Ga-pentixafor.•Increased [68Ga]Ga-pentixafor yield by application of a Multi Generator Tool.•Reduced synthesis time of 14,5 min.•Significant reduction of ethanol content (3,5 ± 0.5 mg/mL).
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ISSN:0969-8043
1872-9800
DOI:10.1016/j.apradiso.2022.110447