Olfactory groove meningiomas: supraorbital keyhole versus orbitofrontal, frontotemporal, or bifrontal approaches

• Published in: Journal of neurosurgery Vol. 140; no. 6; pp. 1 - 8
• Main Authors: Bander, Evan D, Pandey, Abhinav, Yan, Jenny, Giantini-Larsen, Alexandra M, Schwartz, Alexandra, Estin, Joshua, Stieg, Phillip E, Ramakrishna, Rohan, Tsiouris, Apostolos John, Schwartz, Theodore H
• Format: Journal Article
• Language: English
• Published: United States 01-06-2024
• Subjects: meningioma; pterional; olfactory groove; eyebrow; transcranial; supraorbital; skull base; bifrontal; oncology
• ISSN: 0022-3085; 1933-0693; 1933-0693
• DOI: 10.3171/2023.10.JNS231432

Olfactory groove meningiomas (OGMs) often require surgical removal. The introduction of recent keyhole approaches raises the question of whether these tumors may be better treated through a smaller cranial opening. One such approach, the supraorbital keyhole craniotomy, has never been compared with more traditional open transcranial approaches with regard to outcome. In this study, the authors compared clinical, radiographic, and functional quality of life (QOL) outcomes between the keyhole supraorbital approach (SOA) and traditional transcranial approach (TTA) for OGMs. They sought to examine the potential advantages and disadvantages of open/TTA versus keyhole SOA for the resection of OGMs in a relatively case-matched series of patients.
A retrospective, single-institution review of 57 patients undergoing a keyhole SOA or larger traditional transcranial (frontotemporal, pterional, or bifrontal) craniotomy for newly diagnosed OGMs between 2005 and 2023 was performed. Extent of resection, olfaction, length of stay (LOS), radiographic volumetric assessment of postoperative vasogenic and cytotoxic edema, and QOL (using the Anterior Skull Base Questionnaire) were assessed.
Thirty-two SOA and 25 TTA patients were included. The mean EOR was not significantly different by approach (TTA: 99.1% vs SOA: 98.4%, p = 0.91). Olfaction was preserved or improved at similar rates (TTA: 47% vs SOA: 43%, p = 0.99). The mean LOS was significantly shorter for SOA patients (4.1 ± 2.8 days) than for TTA patients (9.4 ± 11.2 days) (p = 0.002). The authors found an association between an increase in postoperative FLAIR cerebral edema and TTA (p = 0.031). QOL as assessed by the ASQB at last follow-up did not differ significantly between groups (p = 0.74).
The keyhole SOA was associated with a statistically significant decrease in LOS and less postoperative edema relative to traditional open approaches.