Risk factors for the development of Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis, following drug administration: a systematic review and meta-analysis
The aim of this systematic review was to determine risk factors for the development of Stevens–Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) following drug administration. The study protocol was registered on PROSPERO. The PRISMA guidelines were followed. On 17 October 2022, a search, advise...
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| Published in: | Clinical and experimental dermatology Vol. 49; no. 12; pp. 1699 - 1704 |
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| Main Authors: | , , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
England
22-11-2024
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| Online Access: | Get full text |
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| Summary: | The aim of this systematic review was to determine risk factors for the development of Stevens–Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) following drug administration. The study protocol was registered on PROSPERO. The PRISMA guidelines were followed. On 17 October 2022, a search, advised by a librarian, was conducted in MEDLINE and Embase. Five studies were pooled. We report that HIV and male gender may be risk factors for SJS/TEN; however, this review was limited by a low number and quality of included studies. We conclude that a well-designed, large population-based case–control study with an appropriate control group is required to assess risk factors for the development of drug-induced SJS/TEN. |
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| Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| ISSN: | 0307-6938 1365-2230 1365-2230 |
| DOI: | 10.1093/ced/llae183 |