U-21,963, a new antibiotic. I. Discovery and biological activity
A new antibiotic, U-21,963, is produced by a new strain of Trichoderma viride. Antibiotic activity can be demonstrated against both gram-positive and gram-negative bacteria and also against a wide variety of fungi. U-21,963 is not cross-resistant with other commonly used antibiotics. U-21,963 afford...
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| Published in: | Applied microbiology Vol. 14; no. 4; pp. 506 - 510 |
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| Main Authors: | , |
| Format: | Journal Article |
| Language: | English |
| Published: |
United States
01-07-1966
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| Subjects: | |
| Online Access: | Get full text |
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| Abstract | A new antibiotic, U-21,963, is produced by a new strain of Trichoderma viride. Antibiotic activity can be demonstrated against both gram-positive and gram-negative bacteria and also against a wide variety of fungi. U-21,963 is not cross-resistant with other commonly used antibiotics. U-21,963 afforded no protection against Klebsiella pneumoniae, Streptococcus pyogenes, or Staphylococcus aureus when it was injected subcutaneously into mice. |
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| AbstractList | A new antibiotic, U-21,963, is produced by a new strain of
Trichoderma viride
. Antibiotic activity can be demonstrated against both gram-positive and gram-negative bacteria and also against a wide variety of fungi. U-21,963 is not cross-resistant with other commonly used antibiotics. U-21,963 afforded no protection against
Klebsiella pneumoniae, Streptococcus pyogenes
, or
Staphylococcus aureus
when it was injected subcutaneously into mice. A new antibiotic, U-21,963, is produced by a new strain of Trichoderma viride. Antibiotic activity can be demonstrated against both gram-positive and gram-negative bacteria and also against a wide variety of fungi. U-21,963 is not cross-resistant with other commonly used antibiotics. U-21,963 afforded no protection against Klebsiella pneumoniae, Streptococcus pyogenes, or Staphylococcus aureus when it was injected subcutaneously into mice. |
| Author | Dietz, A Pyke, T R |
| AuthorAffiliation | Department of Microbiology, The Upjohn Company, Kalamazoo, Michigan |
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| Author_xml | – sequence: 1 givenname: T R surname: Pyke fullname: Pyke, T R – sequence: 2 givenname: A surname: Dietz fullname: Dietz, A |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/4959076$$D View this record in MEDLINE/PubMed |
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| ContentType | Journal Article |
| Copyright | Copyright © 1966 American Society for Microbiology |
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| DOI | 10.1128/am.14.4.506-510.1966 |
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| PublicationTitle | Applied microbiology |
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| PublicationYear | 1966 |
| References | 13355383 - Antibiot Annu. 1955-1956;3:897-902 5927023 - Appl Microbiol. 1966 Jul;14(4):511-2 |
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| Snippet | A new antibiotic, U-21,963, is produced by a new strain of Trichoderma viride. Antibiotic activity can be demonstrated against both gram-positive and... A new antibiotic, U-21,963, is produced by a new strain of Trichoderma viride . Antibiotic activity can be demonstrated against both gram-positive and... |
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| StartPage | 506 |
| SubjectTerms | Anti-Bacterial Agents - pharmacology Culture Media Escherichia coli - drug effects Fungi - drug effects Klebsiella - drug effects Mitosporic Fungi - metabolism Proteus - drug effects Pseudomonas aeruginosa - drug effects Salmonella - drug effects Staphylococcus - drug effects Streptococcus - drug effects |
| Title | U-21,963, a new antibiotic. I. Discovery and biological activity |
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