Involvement of the MPTP in minocycline-induced mitochondrial dysfunction in murine pancreatic acinar cells

Introduction: Mitochondrial dysfunction is a key feature of pancreatic injury leading to acute pancreatitis (AP), which may be mediated via formation of the mitochondrial permeability transition pore (MPTP).

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Bibliographic Details
Published in:	Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] Vol. 13; no. 2; p. e37
Main Authors:	Javed, M.A, Li, W, Collier, D, Jin, T, Huang, W, Awais, M, Tepikin, A, Criddle, D.N, Sutton, R
Format:	Journal Article
Language:	English
Published:	Philadelphia Elsevier B.V 01-03-2013 Elsevier Limited
Subjects:	Apoptosis Endocrinology & Metabolism Gastroenterology and Hepatology Mitochondrial DNA Pancreas Rodents
Online Access:	Get full text
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Description
Summary:	Introduction: Mitochondrial dysfunction is a key feature of pancreatic injury leading to acute pancreatitis (AP), which may be mediated via formation of the mitochondrial permeability transition pore (MPTP).
ISSN:	1424-3903 1424-3911
DOI:	10.1016/j.pan.2012.12.184