Clinical case of disseminated histoplasmosis in a kidney graft recipient

• Published in: Transplantologii͡a Vol. 16; no. 2; pp. 197 - 208
• Main Authors: Titova, P. G., Shmarina, N. V., Lazareva, K. E., Nefedova, G. A., Dmitriev, I. V., Balkarov, A. G.
• Format: Journal Article
• Language: English
• Published: N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department 24-06-2024
• Subjects: fungal infections in kidney graft recipients; histoplasmosis; kidney transplantation
• ISSN: 2074-0506; 2542-0909
• DOI: 10.23873/2074-0506-2024-16-2-197-208

Introduction. Histoplasmosis is not an endemic form of fungal infection in Russia; its sporadic cases are mainly associated with the import of the fungus from endemic countries. We consider it necessary to demonstrate a rare case of the disseminated histoplasmosis development in a kidney transplant recipient.
Objective. Demonstration of a case of the disseminated histoplasmosis development in a kidney transplant recipient.
Results. The clinical manifestations of the disease were described; the affected organs were macroscopically and histologically studied, which made it possible to diagnose disseminated histoplasmosis.
Conclusions. This case prompts being on alert to potential occurrence of fungal infections, including non-endemic ones, in patients receiving immunosuppressive therapy.