Paget's disease of the male breast--report of a case and histopathologic study

We report a 61-year-old male with mammary Paget's disease. Physical examination revealed a slightly exudative erythema at the areola and a reddish, enlarged left nipple. No tumor or left axillary lymph nodes was palpable. He underwent a left modified radical mastectomy. Histologically, there wa...

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Bibliographic Details
Published in:	Journal of dermatology Vol. 16; no. 3; p. 237
Main Authors:	Sano, Y, Inoue, T, Aso, M, Hagari, Y, Hattori, K, Shimao, S, Notsu, T
Format:	Journal Article
Language:	English
Published:	England 01-06-1989
Subjects:	Breast Neoplasms - pathology Breast Neoplasms - surgery Carcinoma, Intraductal, Noninfiltrating - pathology Humans Male Mastectomy, Modified Radical Middle Aged Paget's Disease, Mammary - pathology Paget's Disease, Mammary - surgery Receptors, Estrogen - analysis Receptors, Progesterone - analysis
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Summary:	We report a 61-year-old male with mammary Paget's disease. Physical examination revealed a slightly exudative erythema at the areola and a reddish, enlarged left nipple. No tumor or left axillary lymph nodes was palpable. He underwent a left modified radical mastectomy. Histologically, there was an intraductal carcinoma in the upper portion of the mammary ducts. The axillary lymph nodes that were examined were free of metastasis. Paget cells had neither estrogen nor progesterone receptors. We speculated that the histogenesis of Paget cells involved carcinoma cells that invaded the epidermis of the nipple.
ISSN:	0385-2407
DOI:	10.1111/j.1346-8138.1989.tb01256.x