Rapacuronium

Rapacuronium (Org 9487; ED90 = 1 mg x kg(-1)) is a new, low potency, short-acting, non-depolarizing neuromuscular blocking agent. An intubating dose of 1.5xED90 or 1.5 mg x kg(-1) of rapacuronium offers acceptable intubating conditions within 60-90 s in most patients. A complete block from this dose...

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Bibliographic Details
Published in:Current opinion in anaesthesiology Vol. 13; no. 4; pp. 475 - 478
Main Author: Wierda, J M
Format: Journal Article
Language:English
Published: United States 01-08-2000
Online Access:Get full text
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Summary:Rapacuronium (Org 9487; ED90 = 1 mg x kg(-1)) is a new, low potency, short-acting, non-depolarizing neuromuscular blocking agent. An intubating dose of 1.5xED90 or 1.5 mg x kg(-1) of rapacuronium offers acceptable intubating conditions within 60-90 s in most patients. A complete block from this dose can be reversed immediately with satisfactory recovery in 12-16 min. Side-effects are dose-related and are mainly haemodynamic, i.e. an increase in heart rate and a decrease in blood pressure.
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ISSN:0952-7907
DOI:10.1097/00001503-200008000-00013