COVID-19 Host GenomeDB: A Comprehensive Database Related to COVID-19 Host Genetics

The world is currently faced with a pandemic of coronavirus disease 2019 (COVID-19). Several genome-wide and exome-wide studies (GWAS and EWAS) have been performed to identify the variability in the host genetic constitution that likely underlines the inter-individual variabilities in COVID-19 sever...

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Bibliographic Details
Published in:	International journal of translational medicine Vol. 2; no. 3; pp. 355 - 363
Main Authors:	Banjan, Bhavya, Albeshr, Mohammed F., Mahboob, Shahid, Manzoor, Irfan, Das, Ranajit
Format:	Journal Article
Language:	English
Published:	Jackson MDPI AG 22-07-2022
Subjects:	association studies Chromosomes Coronaviruses COVID-19 COVID-19 database Diabetes Disease Genes genetic variants and genes Genomes Identification documents Literature reviews Medical research Polymorphism Population Structured Query Language-SQL User interface
Online Access:	Get full text
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Summary:	The world is currently faced with a pandemic of coronavirus disease 2019 (COVID-19). Several genome-wide and exome-wide studies (GWAS and EWAS) have been performed to identify the variability in the host genetic constitution that likely underlines the inter-individual variabilities in COVID-19 severity and clinical manifestation. Due to the magnitude of the articles available, creating a list of host-specific genetic variants and genes associated with COVID-19 can be both time-consuming and extremely challenging for COVID-19 researchers. To this end, the COVID-19 Host Genome database was built. This is currently the only dedicated, free-to-use database that deals solely with COVID-19 host-specific genetic variants and genes. HyperText Markup language (HTML), Cascading Style Sheets (CSS), Hypertext Preprocessor (PHP), and My Structured Query Language (MySQL) server (version 5.7.38) were used to develop the website, storage, and extraction of the data. So far, 787 genetic variants from 63 previously published articles were collected. The tabular data are hyperlinked to the original articles and the users can download all data from the database. COVID-19 Host GenomeDB is being revised constantly every month, and can benefit the research community studying the genetic variants to improve COVID-19 treatment and prevention strategies.
ISSN:	2673-8937 2673-8937
DOI:	10.3390/ijtm2030028