Research of effects of plant preparation with integrated action in cough therapy in school children

• Published in: Medicinskij sovet no. 1; pp. 100 - 107
• Main Authors: Rashitova, Elina L., Zakirova, Alfiia M., Moroz, Tatyana B., Shayapova, Dilyara T. S, Kadriev, Albert G., Kadriev, Amir G.
• Format: Journal Article
• Language: English; Russian
• Published: Remedium Group LLC 21-03-2021
• Subjects: cough therapy; efficiency; herbal preparation; safety; schoolchildren
• ISSN: 2079-701X; 2658-5790
• DOI: 10.21518/2079-701X-2021-1-100-107

Introduction. Cough accompanies an acute infectious process in the respiratory tract. The article focuses on the symptomatic treatment of cough using a modern herbal preparation with complex action and standard therapy.
Goal. To study the effects of a herbal preparation with complex action in the treatment of cough in children.
Materials and methods. The study included 72 patients of both sexes (mean age 14.6 ± 2.3 years) with a symptom of unproductive/unproductive cough, against the background of acute bronchitis or community-acquired pneumonia.
Results and discussion. When using a herbal preparation with complex action was used in ¾ of the children, cough decreased by the 3rd day and in most patients it stopped by the 10 th day. The severity of daytime and nighttime coughs decreased by 3.0–3.5 points, the number of seizures decreased to 2–4 per day, the duration of seizures also decreased significantly, the median of this indicator in the main group reached 0 points. In both groups, the proportion of patients with seizure frequency of no more than 4 per day increased. While taking a herbal preparation, a more pronounced decrease in all indicators of cough by 3.5 times was noted throughout the treatment, and the corresponding effects developed 3 days ahead of time against the background of a full course of therapy. The average value of the efficacy and safety assessment given by the medical researchers to the action of the herbal preparation with complex action was 3.6 points. Analysis of objective and subjective data based on the results of evaluating case histories and individually developed questionnaires for patients on drug tolerance showed equivalence in terms of excellent and good results. Against the background of the full course of treatment with the herbal preparation, a 1.8 times more pronounced decrease in the characteristics of the cough syndrome was noted.
Conclusion. The drug has shown high efficacy and safety, which makes it possible to recommend it as a symptomatic therapy for cough in school-age children as part of a combination or monotherapy.