Influence of ion interactions on the conformation of ribozyme specific to HIV-1 tat-RNA in solution

Using the method of partial nudease hydrolysis it was shown that the medium ion composition essentially influenced tertiary interactions in the ribozyme molecule and changed its spatial structure.

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Bibliographic Details
Published in:Biopolimery i kletka Vol. 18; no. 5; pp. 452 - 454
Main Authors: Markelova, O. Yu, Buryanovsky, L. N., Kitam, O. E., Krasnova, K. F., Shved, A. D.
Format: Journal Article
Language:English
Published: Kiev Natsional'na Akademiya Nauk Ukrainy - National Academy of Sciences of Ukraine 2002
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Description
Summary:Using the method of partial nudease hydrolysis it was shown that the medium ion composition essentially influenced tertiary interactions in the ribozyme molecule and changed its spatial structure.
ISSN:0233-7657
1993-6842
DOI:10.7124/bc.000627