Mean Platelet Volume, Neutrophil Lymphocyte Ratio and Platelet Lymphocyte Ratio to Predict Complications During Postoperative Recovery of High Risk Surgical Patients

• Published in: Bagcilar Medical Bulletin Vol. 6; no. 4; pp. 382 - 389
• Main Authors: Balkan, Bedih, Çelik, Mustafa, Tok Çekmecelioğlu, Büşra, Yavuz, Damla, Altun, Dilek, Hergünsel, Gülsüm Oya
• Format: Journal Article
• Language: English
• Published: Galenos Yayinevi 12-12-2021
• Subjects: asa-3 cases; complication; intensive care; mean platelet volume; neutrophil-lymphocyte ratio; platelet-lymphocyte ratio
• ISSN: 2547-9431; 2547-9431
• DOI: 10.4274/BMB.galenos.2021.04.052

Objective:This study sought to define the correlation between the occurrence of the complications and certain blood parameters in high risk surgical patients who were monitored for 24 hours in the intensive care unit postoperatively.Method:Two hundred-fifty seven cases (126 females 131 males; mean age 42.18±8.54 years; range 19-73 years) who were operated on in our hospital and followed up in the intensive care unit for 24 hours were included in this study. The files of all cases included demographic characteristics, erythrocyte count (RBC), leukocyte count (WBC), platelet count (PLT), mean platelet volume (MPV), neutrophil, lymphocyte, neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), serum blood urea nitrogen (BUN) and creatinine values. Group A consisted of cases that did not develop complications in the first 24 hours, and group B consisted of cases that developed complications in the first 24 hours postoperatively. The blood hemogram parameters RBC, WBC, PLT, MPV, NLO, PLO, and the biochemistry parameters BUN and creatinine were compared between the groups.Results:Preoperative MPV value and postoperative MPV value were significantly higher in group B than group A (p-values 0.038 and 0.045, respectively). In groups A and B, the postoperative MPV value increased significantly compared to the preoperative period (p=0.032, p=0.000, respectively). Preoperative PLR and postoperative PLR values did not differ significantly in groups A and B (p=0.101 and p=0.458, respectively). The postoperative PLR value increased significantly in groups A and B compared to the preoperative period (p=0.000 and p=0.047, respectively) Preoperative and postoperative NLR values in group B were significantly higher than group A (p=0.006 and p=0.025 respectively). In groups A and B, the postoperative NLR value increased significantly compared to the preoperative period (p=0.000 and p=0.006, respectively).Conclusion:In this study, the cases that developed complications had more significant increases in their MPV, NLR, and PLR values during the postoperative period than their counterparts who experienced no complications.