P71 – 2336: Brain and spinal MR imaging findings in metachromatic leukodystrophy: Enhancing cranial nerves and cauda equina

• Published in: European journal of paediatric neurology Vol. 19; p. S114
• Main Authors: Alkan, O, Erol, I, Saygi, S
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01-05-2015
• Subjects: Neurology; Pediatrics
• ISSN: 1090-3798; 1532-2130
• DOI: 10.1016/S1090-3798(15)30384-6

Objective To present contrast-enhanced brain and spinal MR imaging findings two patients with metachromatic leukodystrophy (MLD). Methods The patients presented with walking and speech disorders. The patients underwent contrast-enhanced brain and lumbar spine MR imaging. Results T2-weighted images of the brain showed abnormal hyperintensity in the deep and periventricular white matter. Postcontrast T1-weighted images of the brain showed enhancement of the cranial nerves. Postcontrast T1-weighted images of the lumbar spine displayed enhancement of the cauda equina. Conclusion MLD is one of the more common leukodystrophies with well-documented white matter findings. The contrast enhancement of cranial nerves and cauda equina may accompany the white matter findings of MLD. Contrast-enhanced brain and spinal MR imaging may prove useful in diagnosing or differentiating the various leukodystrophies.