Chronic Obstructive Pulmonary Disease: Biofilm Mediated Exacerbation and Innovative Therapeutic Approaches

Chronic Obstructive Pulmonary Disease: Biofilm Mediated Exacerbation and Innovative Therapeutic Approaches

Chronic obstructive pulmonary disease (COPD) is a leading cause of death. The prevalence of the disease and associated mortality continue to increase. Bacterial and viral infections are responsible for the transition of the disease to more severe stages, resulting in COPD exacerbation. Biofilms, com...

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Bibliographic Details
Published in:European medical journal. Respiratory pp. 99 - 107
Main Authors: Berger, Irene, Kagan, Adina, Bock, Rebecca, Loewy, Zvi G.
Format: Journal Article
Language:English
Published: European Medical Journal 24-10-2023
Online Access:Get full text
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Summary:Chronic obstructive pulmonary disease (COPD) is a leading cause of death. The prevalence of the disease and associated mortality continue to increase. Bacterial and viral infections are responsible for the transition of the disease to more severe stages, resulting in COPD exacerbation. Biofilms, communities of micro-organisms that contribute to COPD exacerbation, pose a formidable challenge for effective pharmacotherapy. This review focuses on the development of biofilms, and approaches to inhibit and eradicate biofilms.
ISSN:2054-3166
2054-3166
DOI:10.33590/emjrespir/10305099