The Modification of Anti-Inflammatory Properties of the Combined use of Nsaids and Glucosamine in Topical Dosage Form for Degenerative and Inflammatory Joint Diseases Treatment

The Modification of Anti-Inflammatory Properties of the Combined use of Nsaids and Glucosamine in Topical Dosage Form for Degenerative and Inflammatory Joint Diseases Treatment

The study on the cotton wool granuloma model in rats showed that the combination had moderate antiproliferative activity of 33.4% and was significantly inferior to ketoprofen gel 2.5%, which had activity of 41.4%, but significantly prevalent chondroitin sulfate gel 5.0%, which had activity of 18.0%.

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Bibliographic Details
Published in:Clinical therapeutics Vol. 38; no. 10; p. e24
Main Authors: Davishnia, N.V, Zupanets, I.A, Shebeko, S.K, Lyapunov, M.O
Format: Journal Article
Language:English
Published: United States Elsevier Limited 01-10-2016
Subjects:
Chondroitin sulfate
Edema
Internal Medicine
Medical Education
Rodents
Studies
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Description
Summary:The study on the cotton wool granuloma model in rats showed that the combination had moderate antiproliferative activity of 33.4% and was significantly inferior to ketoprofen gel 2.5%, which had activity of 41.4%, but significantly prevalent chondroitin sulfate gel 5.0%, which had activity of 18.0%.
ISSN:0149-2918
1879-114X
DOI:10.1016/j.clinthera.2016.07.144