Knowledge and awareness of human papillomavirus (HPV) influence HPV vaccination uptake among the catch-up generation in Japan

• Published in: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy
• Main Authors: Yamagishi, Yuka, Nakamura, Natsuko, Minami, Marina, Keyama, Kaoru, Osaka, Kyoko, Maeda, Nagamasa, Mikamo, Hiroshige
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 21-09-2024
• Subjects: Awareness; Catch-up vaccination; Cervical cancer; Disease knowledge; Education; HPV vaccination; OR; HPV vaccination; aOR; Awareness; CI; cOR; HPV; FY; Education; Catch-up vaccination; Disease knowledge; Cervical cancer; WHO
• ISSN: 1341-321X; 1437-7780; 1437-7780
• DOI: 10.1016/j.jiac.2024.09.016

Despite its importance for young women, the human papillomavirus (HPV) vaccination coverage remains low in Japan. Previous studies have examined behaviors related to HPV catch-up vaccination. Uniquely, this study aimed to investigate perceptions and factors influencing vaccination coverage among female university students in the catch-up program, focusing on both medical and non-medical undergraduates.
A web-based survey was conducted at Kochi University from January 16 to February 13, 2023, targeting female students born between April 2, 1997, and April 1, 2006. The survey collected demographic data and assessed knowledge of HPV infection, cervical cancer, and preventive measures. Chi-square tests and logistic regression analyses were used to identify differences between vaccinated and unvaccinated groups as well as factors related to HPV vaccination.
Of the 310 participants, 39.0 % were vaccinated against HPV, 35.2 % were freshmen, and 75.2 % were in medical science programs. HPV vaccination was significantly associated with being in upper years of university (OR = 3.78–42.83), studying medical sciences (OR = 1.93), undergoing cervical cancer screening (OR = 4.04), and receiving free vaccination vouchers (OR = 2.03).
Knowledge and awareness of HPV and cervical cancer significantly contribute to higher vaccination uptake in the generation receiving catch-up vaccinations. Tailoring information and distributing free vaccination vouchers could enhance HPV vaccination rates and awareness in this group.