Malignant melanoma arising in an in vitro fertilisation pregnancy: A case report

• Published in: Journal of the Turkish German Gynecological Association Vol. 14; no. 3; pp. 186 - 187
• Main Authors: Pabuccu, Recai, Kiseli, Mine, Kahyaoglu, Inci, Caglar, Gamze Sinem, Yilmaz, Muserref Banu
• Format: Journal Article
• Language: English
• Published: AVES 10-07-2013
• Subjects: Case Report
• ISSN: 1309-0399; 1309-0380
• DOI: 10.5152/jtgga.2013.22804

Malignant melanoma diagnosed during pregnancy results in confusion about staging and management. In this case report, a 39-year-old pregnant woman, who had undergone conception via
in vitro
fertilisation, was diagnosed with malignant melanoma of a growing lesion on her back in the 20th week of gestation. She delivered her baby by caesarean section in the 38th week. Metastasis was not found by chest X-ray, ultrasonography and positron emission tomography after delivery. She has been disease free for 6 months postpartum. Surgical resection of malignant melanoma and postponing of the sentinel lymph node biopsy has been proposed. Risk of adverse perinatal outcomes has not been increased; but the prognosis of malignant melanoma is known to be poorer when diagnosed during pregnancy. As a conclusion, any pigmentary change in the nevi should be assessed carefully during pregnancy.