Hematology Emergencies in Critically Ill Adults

Hematologic conditions (malignant or benign) may progress to acute critical illness requiring prompt recognition and intensive management. This review outlines diagnostic considerations and approaches to management for intensivists of common benign hematologic emergencies, including the following: t...

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Bibliographic Details
Published in:	Chest Vol. 161; no. 5; pp. 1285 - 1296
Main Authors:	Spring, Jenna, Munshi, Laveena
Format:	Journal Article
Language:	English
Published:	Elsevier Inc 01-05-2022
Subjects:	antiphospholipid syndrome disseminated intravascular coagulation hematologic emergencies hemophagocytic lymphohistiocytosis thrombotic thrombocytopenic purpura APS vWF HLH aHUS TPE hemophagocytic lymphohistiocytosis IVIG TMA thrombotic thrombocytopenic purpura ST-HUS antiphospholipid syndrome TTP SCD hematologic emergencies HbS disseminated intravascular coagulation CAPS DIC
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Summary:	Hematologic conditions (malignant or benign) may progress to acute critical illness requiring prompt recognition and intensive management. This review outlines diagnostic considerations and approaches to management for intensivists of common benign hematologic emergencies, including the following: thrombotic thrombocytopenic purpura, atypical hemolytic uremic syndrome, disseminated intravascular coagulopathy, catastrophic antiphospholipid antibody syndrome, hemophagocytic lymphohistiocytosis, acute chest syndrome associated with sickle cell disease, and hyperhemolysis syndrome.
ISSN:	0012-3692 1931-3543
DOI:	10.1016/j.chest.2021.12.650