The Effect of Dopamine on Functional Connectivity, Working Memory and Individual Differences

While low WM capacity individuals improve on WM tasks with dopaminergic agonists, performance in high WM capacity individuals worsens (Kimberg, D'Esposito and Farah, 1997). [...]we have shown that WM capacity predicts dopamine synthesis, with high WM capacity individuals showing greater striata...

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Bibliographic Details
Published in:NeuroImage (Orlando, Fla.) Vol. 47; p. S167
Main Authors: Wallace, DL, Vytlacil, JJ, Gibbs, SEB, Nomura, EM, D'Esposito, MT
Format: Journal Article
Language:English
Published: Amsterdam Elsevier Inc 01-07-2009
Elsevier Limited
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Summary:While low WM capacity individuals improve on WM tasks with dopaminergic agonists, performance in high WM capacity individuals worsens (Kimberg, D'Esposito and Farah, 1997). [...]we have shown that WM capacity predicts dopamine synthesis, with high WM capacity individuals showing greater striatal dopamine levels (Cools et al., 2008).
ISSN:1053-8119
1095-9572
DOI:10.1016/S1053-8119(09)71781-1