Identification of novel SEC61G-EGFR fusions in pediatric ependymoma

Identification of novel SEC61G-EGFR fusions in pediatric ependymoma

An abstract of a study by Servidei et al assessing identification of novel SEC61G-EGFR fusions in pediatric ependymoma is presented. Compared to EPR EPP-MI cells displayed impaired proliferation in vitro, but much higher tumorigenicity, despite a lower expression of sternness markers.

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Bibliographic Details
Published in:European journal of cancer (1990) Vol. 69; p. S51
Main Authors: Servidei, T, Meco, D, Muto, V, Tartaglia, M, Riccardi, R
Format: Journal Article
Language:English
Published: Oxford Elsevier Science Ltd 01-12-2016
Subjects:
Cell proliferation
Epidermal growth factor receptors
Hematology, Oncology and Palliative Medicine
Medical treatment
Pediatrics
Tumorigenicity
Tumors
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Description
Summary:An abstract of a study by Servidei et al assessing identification of novel SEC61G-EGFR fusions in pediatric ependymoma is presented. Compared to EPR EPP-MI cells displayed impaired proliferation in vitro, but much higher tumorigenicity, despite a lower expression of sternness markers.
ISSN:0959-8049
1879-0852
DOI:10.1016/S0959-8049(16)32738-1