Preparation, structure and bioactivity of xAu₂O₃·(100−x)[P₂O₅·CaO] glass system

• Published in: Journal of molecular structure Vol. 1006; no. 1-3; pp. 312 - 317
• Main Authors: Regos, Adriana N, Ardelean, I
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01-12-2011
• Subjects: absorption; apatite; bioactive properties; biocompatible materials; blood plasma; calcium oxide; glass; humans; melting; Raman spectroscopy; scanning electron microscopes; soaking; temperature; thermal analysis; X-ray diffraction
• ISSN: 0022-2860; 1872-8014
• DOI: 10.1016/j.molstruc.2011.09.025

Gold doped calcium phosphate glasses were prepared by the melting method. The structure of Au₂O₃–P₂O₅–CaO glasses is investigated using X-ray diffraction, infrared absorption and Raman scattering. The depth characterization of their structures is essential for the understanding of the properties of biocompatible materials. Thermal analysis DTA and TGA were also made to study behavior under different temperature regions and to see chemical changes versus time and temperature of these glasses. Bioactivity of the glasses was investigated in vitro by examining apatite formation on the surface of glasses treated in acellular simulated body fluid (SBF) with ion concentrations nearly equal to those in human blood plasma. Formation of bioactive apatite layer on the samples treated in SBF for 28days at 37°C was confirmed by X-ray diffraction (XRD) and scanning electron microscope (SEM). The effect of SBF soaking induces structural changes on the surface, reflected by the appearance of nano-crystalline particles agglomerated into micro-aggregates.