Complete Nucleotide Sequence of pKOI-34, an IncL/M Plasmid Carrying bla IMP-34 in Klebsiella oxytoca Isolated in Japan

• Published in: Antimicrobial agents and chemotherapy Vol. 60; no. 5; pp. 3156 - 3162
• Main Authors: Shimada, Norimitsu, Kayama, Shizuo, Shigemoto, Norifumi, Hisatsune, Junzo, Kuwahara, Ryuichi, Nishio, Hisaaki, Yamasaki, Katsutoshi, Wada, Yasunao, Sueda, Taijiro, Ohge, Hiroki, Sugai, Motoyuki
• Format: Journal Article
• Language: English
• Published: 01-05-2016
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.02507-15

We determined the complete nucleotide sequence of a self-transmissible IncL/M plasmid, pKOI-34, from a
Klebsiella oxytoca
isolate. pKOI-34 possessed the core structure of an IncL/M plasmid found in
Erwinia amylovora
, pEL60, with two mobile elements inserted, a transposon carrying the arsenic resistance operon and a Tn
21
-like core module (
tnp
and
mer
modules) piggybacking
bla
IMP-34
as a class 1 integron, In
808
, where
bla
IMP-34
confers a resistance to carbapenems in
K. oxytoca
and
Klebsiella pneumoniae
.