Multipurpose On‐the‐Spot Peptide‐Based Hydrogels for Skin, Cornea, and Heart Repair (Adv. Funct. Mater. 37/2024)

• Published in: Advanced functional materials Vol. 34; no. 37
• Main Authors: Ross, Alex, Guo, Xixi, Salazar, German A. Mercado, Schejtman, Sergio David Garcia, El‐Hage, Jinane, Comtois‐Bona, Maxime, Macadam, Aidan, Guzman‐Soto, Irene, Takaya, Hiroki, Hu, Kevin, Liu, Bryan, Tu, Ryan, Siddiqi, Bilal, Anderson, Erica, Muñoz, Marcelo, Briones‐Rebolledo, Patricio, Ning, Tianqin, Griffith, May, Rotsein, Benjamin, Poblete, Horacio, Li, Jianyu, Ruel, Marc, Suuronen, Erik J., Alarcon, Emilio I.
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc 01-09-2024
• Subjects: Biomedical materials; biomimetic materials; Chemical synthesis; Cornea; Hydrogels; Peptides; regenerative therapies; soft tissue repair
• ISSN: 1616-301X; 1616-3028
• DOI: 10.1002/adfm.202470212

Peptide‐Based Hydrogels
In article number 2402564, Marc Ruel, Erik J. Suuronen, Emilio I. Alarcon, and co‐workers develop a minimalistic and versatile biomaterial that rapidly gels on the spot using click chemistry and supramolecular assembly of custom‐designed collagen‐like peptides. After screening through a library of custom peptides, top candidate formulations are tested to repair skin and cornea and as a delivery system for treating infarcted heart muscle.