The detection of the 25B-NBOMe derivative of phenylethylamine in the biological material

This article is focused on the conditions for the detection and identification of 2-[4-bromo-2.5-dimethoxyl]-N-[(2-methoxyphenyl)methyl] ethamine (25B-NBOMe) and its major metabolites by the combination of the HPLC/MS/MS techniques. The high-resolution mass spectra obtained with the use of a linear...

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Published in:Sudebno-meditsinskaia ekspertiza Vol. 62; no. 2; p. 34
Main Authors: Barsegyan, S S, Kiryushin, A N, Eroshchenko, N N, Tuaeva, N O, Nosyrev, A E, Kirilyuk, A A
Format: Journal Article
Language:English
Russian
Published: Russia (Federation) 2019
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Abstract This article is focused on the conditions for the detection and identification of 2-[4-bromo-2.5-dimethoxyl]-N-[(2-methoxyphenyl)methyl] ethamine (25B-NBOMe) and its major metabolites by the combination of the HPLC/MS/MS techniques. The high-resolution mass spectra obtained with the use of a linear ion trap are described. The results of the study give evidence of the possibility for the detection of the analytes within 24 hours after drug consumption and within 3 months after the storage of the biological material of interest in a refrigerator at a temperature of 3-5 °C. The data obtained confirmed high stability of 2-(4-bromo-2.5-dimethoxyl]-N-[(2-methoxyphenyl)methyl] ethamine and its metabolites in the biological tissues.
AbstractList This article is focused on the conditions for the detection and identification of 2-[4-bromo-2.5-dimethoxyl]-N-[(2-methoxyphenyl)methyl] ethamine (25B-NBOMe) and its major metabolites by the combination of the HPLC/MS/MS techniques. The high-resolution mass spectra obtained with the use of a linear ion trap are described. The results of the study give evidence of the possibility for the detection of the analytes within 24 hours after drug consumption and within 3 months after the storage of the biological material of interest in a refrigerator at a temperature of 3-5 °C. The data obtained confirmed high stability of 2-(4-bromo-2.5-dimethoxyl]-N-[(2-methoxyphenyl)methyl] ethamine and its metabolites in the biological tissues.
Author Tuaeva, N O
Kirilyuk, A A
Kiryushin, A N
Nosyrev, A E
Barsegyan, S S
Eroshchenko, N N
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  surname: Barsegyan
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  givenname: A N
  surname: Kiryushin
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  organization: Central Chemical Toxicological Laboratory, I.M. Sechenov First Moscow State Medical University, Moscow, Russia, 119435; Analytical Toxicology V.P. Serbskiy Federal Medical Research Centre of Psychiatry and Narcology, Moscow, Russia, 119002
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  surname: Eroshchenko
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  organization: Central Chemical Toxicological Laboratory, I.M. Sechenov First Moscow State Medical University, Moscow, Russia, 119435; Analytical Toxicology V.P. Serbskiy Federal Medical Research Centre of Psychiatry and Narcology, Moscow, Russia, 119002
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  givenname: A E
  surname: Nosyrev
  fullname: Nosyrev, A E
  organization: Central Chemical Toxicological Laboratory, I.M. Sechenov First Moscow State Medical University, Moscow, Russia, 119435; Analytical Toxicology V.P. Serbskiy Federal Medical Research Centre of Psychiatry and Narcology, Moscow, Russia, 119002
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  givenname: A A
  surname: Kirilyuk
  fullname: Kirilyuk, A A
  organization: Laboratory of Metrological Support of Biological and Information Technologies, All-Russian Research Institute of Metrological Services, Moscow, Russia, 119361
BackLink https://www.ncbi.nlm.nih.gov/pubmed/31213590$$D View this record in MEDLINE/PubMed
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DocumentTitleAlternate Obnaruzhenie 25B-NBOMe - proizvodnogo fenilétilamina v biologicheskom materiale
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Keywords narcotic drugs
metabolites
25B-NBOMe
tandem mass-spectrometry
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Russian
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Snippet This article is focused on the conditions for the detection and identification of 2-[4-bromo-2.5-dimethoxyl]-N-[(2-methoxyphenyl)methyl] ethamine (25B-NBOMe)...
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StartPage 34
SubjectTerms Anisoles - analysis
Chromatography, High Pressure Liquid
Forensic Sciences - methods
Phenethylamines - analysis
Tandem Mass Spectrometry
Title The detection of the 25B-NBOMe derivative of phenylethylamine in the biological material
URI https://www.ncbi.nlm.nih.gov/pubmed/31213590
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