Infection‐responsive polysaccharide‐based drug‐loaded nano‐assembly for dual‐modal treatment against drug‐resistant bacterial lung infection (3/2024)

Infection‐responsive polysaccharide‐based drug‐loaded nano‐assembly for dual‐modal treatment against drug‐resistant bacterial lung infection (3/2024)

In this article number 10.1002/bmm2.12120, a kind of infection‐responsive drug‐loaded nano‐assembly, STQ12, was developed by the electrostatic interaction between negatively charged polysaccharide and positively charged quaternized ammonium salt polymer. STQ12 could penetrate the mucus layer rapidly...

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Bibliographic Details
Published in:BMEmat (Print) Vol. 2; no. 3
Main Authors: Han, Lin, Yuan, Zhonghua, Ren, Hui‐Min, Song, Weizhuo, Wu, Ruonan, Li, Jie, Guo, Zhaoyan, Yu, Bingran, Duan, Shun, Xu, Fu‐Jian
Format: Journal Article
Language:English
Published: 01-09-2024
Online Access:Get full text
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Summary:In this article number 10.1002/bmm2.12120, a kind of infection‐responsive drug‐loaded nano‐assembly, STQ12, was developed by the electrostatic interaction between negatively charged polysaccharide and positively charged quaternized ammonium salt polymer. STQ12 could penetrate the mucus layer rapidly and reach the acidic microenvironment at the infected site, releasing the loaded drug and QPEI‐C6 to realize combined anti‐infection therapy against multi‐drug resistant bacteria.
ISSN:2751-7438
2751-7446
DOI:10.1002/bmm2.12120