0840 Longitudinal Association Of Objective Sleep Duration, Timing, And Regularity With Weight Change In HCHS/SOL Sueño Ancillary Study

• Published in: Sleep (New York, N.Y.) Vol. 42; no. Supplement_1; p. A337
• Main Authors: Vetter, Celine, Fritz, Josef, Downer, Kendra, Phillips, Andrew J K, Zee, Phyllis, Baron, Kelly Glazer, Redline, Susan, Mossavar-Rahmani, Yasmin, Petrov, Megan E, Reid, Kathryn J, Sotres-Alvarez, Daniela, Patel, Sanjay R
• Format: Journal Article
• Language: English
• Published: Westchester Oxford University Press 13-04-2019
• Subjects: Hispanic Americans; Sleep
• ISSN: 0161-8105; 1550-9109
• DOI: 10.1093/sleep/zsz067.838

Introduction We examined the prospective association between objective sleep and weight change in a representative sample of Hispanic/Latinos in the US. We expected shorter sleep, later sleep timing, and more irregular sleep to be associated with higher weight change across ~6 years follow-up. Methods Baseline and follow-up weight was available in 1,859 Hispanic Community Health Study/Study of Latinos Sueño participants (after outlier exclusion; mean weighted age: 42.1 years, 45% male), and baseline one-week wrist actigraphy was used to quantify sleep duration, timing, and regularity (Sleep Regularity Index [SRI]; range: 0-100 from least to more regular). We used complex survey regression methods to examine prospective associations of quartiles of each sleep metric with weight change (continuously) and weight gain (>5kg), adjusting for age, sex, ethnic background, site, marital status, depressive symptoms, income, education, the other sleep dimensions, and time between assessments. Results Average weight change across follow-up was +0.11kg. We did not observe significant statistical associations of sleep duration, timing, or regularity with continuous weight change or categorical weight gain, but estimates suggested associations in the hypothesized directions. We also did not observe evidence for effect modification of the association between sleep and weight change by baseline overweight status (body mass index [BMI] <25 vs. >= 25). Amongst participants with no weight change or weight gain throughout follow-up (N=873), more regular sleep was associated with less weight gain after multi-variable adjustment (Q1 vs. Q4= -0.85kg, 95% confidence interval -1.74;0.03; ptrend=0.04). Conclusion Overall, we did not observe significant associations between baseline objective estimates of sleep and 6-year prospective weight change. Possible explanations include that we were limited to a single assessment of sleep behavior, small effect size, and/or limited statistical power. Future studies with repeated exposure and outcome measures are needed to evaluate the role of changes in sleep behaviors over time to overweight, obesity and weight gain. Support (If Any) NIH HL098927