Influence of the resolution mode on mean and maximum SUV for PET images acquired by a LabPET SOLO 4 scanner

• Published in: Brazilian Journal of Radiation Sciences Vol. 11; no. 3; pp. 1 - 11
• Main Authors: Barbosa, João Vitor do Carmo, Souza, Guilherme Cavalcante Albuquerque de, Gontijo, Rodrigo Modesto Gadelha, Mendes, Bruno Melo, Ferreira, Andrea Vidal
• Format: Journal Article
• Language: English
• Published: Brazilian Radiation Protection Society (Sociedade Brasileira de Proteção Radiológica, SBPR) 24-08-2023
• Subjects: LabPET SOLO 4; Resolution Mode; Standardized Uptake Value
• ISSN: 2319-0612; 2319-0612
• DOI: 10.15392/2319-0612.2023.2273

In preclinical PET, SUV (standardized uptake value) is a robust quantifier that can be used to analyze PET images. Several factors – biological or technical – can affect SUV determination. Among technical factors, it is possible to cite the reconstruction protocols of PET images. This work evaluated the influence of two resolution modes – standard and high – on mean and maximum SUVs. The PET image of a mouse with a tumor in left flank was chosen from a PET image bank and reconstructed using two different protocols varying the resolution mode. The post-processing of images was performed using AMIDE software and eight volumes of interest (VOIs) were defined. Qualitatively, there was light improvement in structures definition in high-resolution image compared to standard resolution image. At the semiquantitative analysis, image reconstruction protocols using high-resolution mode did not significantly improve the recuperation of radiopharmaceutical uptake into analyzed tissues.