BS03
PATTERNS AND PROGNOSIS OF BREAST CANCER RECURRENCE

• Published in: ANZ journal of surgery Vol. 77; no. s1; p. A1
• Main Authors: Gillett, D. J., Elder, E., Gluch, L., Carmalt, H. C.
• Format: Journal Article
• Language: English
• Published: Melbourne, Australia Blackwell Publishing Asia 01-05-2007
• ISSN: 1445-1433; 1445-2197
• DOI: 10.1111/j.1445-2197.2007.04114_3.x

The data base of The Strathfield Breast Centre (TSBC) was reviewed to determine the patterns of recurrence and their prognosis after the treatment of breast cancer.
The TSBC has a prospective data base from 1989 forward with information on 2509 patients up to 2002. The follow‐up on these patients is 81%. This data was interrogated.
Breast conservation was performed in 1390 (55.4%) and of these 84.7% had adjuvant radiotherapy and 62.7% had adjuvant systemic treatment. Rates of recurrence were related to grade and stage of the tumour.
Local regional or distant relapse occurred in 456 (18%). The site of first cancer recurrence was local 27.2%, bone 27.4%, lung 16% liver 12.5% and supraclavicular fossa 5.5%.
At the end of the study 527 patients had died, 323 were cancer related deaths, the majority of the recurrences occurred in the first three years (58%) and 79% occurred within 5 years.
Local recurrence in the breast occurred in 4.6% of patients and in the chest wall in 5.2%. The 5 yr disease free survival of these patients was 49.4% and 33.1% respectively.
Distant metastases occurred to bone, lung and liver in the majority of cases in which it happened. The 5 yr survival for these patients was16%, 12% and 0%.
The recurrence data from the TSBC is comparable to that reported elsewhere. The majority of recurrences occurr in the first 5 yrs, The prognosis after relapse varies with site.Local in the b reast being better than in the chest wall and bone being better than visceral.