Optimal prevention of VTE in cancer surgery patients with impaired renal function

• Published in: Hirurgija (Moskva) no. 1; p. 119
• Main Authors: Katelnitskaya, O V, Barashev, A A, Ausheva, T V
• Format: Journal Article
• Language: English; Russian
• Published: Russia (Federation) 2024
• Subjects: Anticoagulants - adverse effects; Humans; Kidney; Neoplasms - complications; Neoplasms - surgery; Renal Insufficiency; Veins; Venous Thromboembolism - diagnosis; Venous Thromboembolism - etiology; Venous Thromboembolism - prevention & control; surgical treatment; fondaparinux; impaired renal function; oncology; venous thromboembolic events
• ISSN: 0023-1207
• DOI: 10.17116/hirurgia2024011119

Despite notable progress in the prevention of venous thromboembolic complications (VTE) and its widespread use in recent decades, mortality in cancer patients from VTE is still second only to the main disease. Some features and limitations in cancer patients, such as a decrease in kidney function and platelet count, an increased risk of bleeding, and the difficulty of monitoring the adequacy and safety of thromboprophylaxis, as well as the use of aggressive chemotherapy, determine the need for more effective and safer ways to solve the problem of VTE. Also, in the case of surgical interventions in such patients, the need for preoperative thromboprophylaxis raises new challenges for doctors. The article presents a review of the issue using a clinical case.