Randomised controlled trial of a short course of traditional acupuncture compared with usual care for persistent non-specific low back pain

• Published in: BMJ Vol. 333; no. 7569; pp. 623 - 626
• Main Authors: Thomas, K J, MacPherson, H, Thorpe, L, Brazier, J, Fitter, M, Campbell, M J, Roman, M, Walters, S J, Nicholl, J
• Format: Journal Article
• Language: English
• Published: London British Medical Journal Publishing Group 23-09-2006; British Medical Association; BMJ Publishing Group LTD; BMJ Publishing Group; BMJ Publishing Group Ltd
• Edition: International edition
• Subjects: Acupuncture; Acupuncture Therapy - methods; Adolescent; Adult; Aged; Alternative medicine; Analgesics; Back pain; Biological and medical sciences; Chronic Disease; Clinical trials; Disabilities; Diseases of the osteoarticular system; Diseases of the spine; Female; General aspects; Health care outcome assessment; Health outcomes; Humans; Low back pain; Low Back Pain - therapy; Male; Medical sciences; Middle Aged; Pain; Pain management; Pain Measurement; Primary care; Primary health care; Quality of Life; Statistical results; Treatment Outcome; United Kingdom > UK; England; Lumbar spine; Oriental medicine; Low back pain; Diseases of the osteoarticular system; Spine disease; Care; Pain; Treatment; Folk medicine; Randomised controlled trial; Rachialgia; Clinical trial; Acupuncture; Comparative study
• ISSN: 0959-8138; 0959-8146; 1468-5833; 1756-1833
• DOI: 10.1136/bmj.38878.907361.7C

Abstract Objective To determine whether a short course of traditional acupuncture improves longer term outcomes for patients with persistent non-specific low back pain in primary care. Design Pragmatic, open, randomised controlled trial. Setting Three private acupuncture clinics and 18 general practices in York, England. Participants 241 adults aged 18-65 with non-specific low back pain of 4-52 weeks' duration. Interventions 10 individualised acupuncture treatments from one of six qualified acupuncturists (160 patients) or usual care only (81 patients). Main outcome measures The primary outcome was SF-36 bodily pain, measured at 12 and 24 months. Other outcomes included reported use of analgesics, scores on the Oswestry pain disability index, safety, and patient satisfaction. Results 39 general practitioners referred 289 patients of whom 241 were randomised. At 12 months average SF-36 pain scores increased by 33.2 to 64.0 in the acupuncture group and by 27.9 to 58.3 in the control group. Adjusting for baseline score and for any clustering by acupuncturist, the estimated intervention effect was 5.6 points (95% confidence interval −0.2 to 11.4) at 12 months (n = 213) and 8.0 points (2.8 to 13.2) at 24 months (n = 182). The magnitude of the difference between the groups was about 10%-15% of the final pain score in the control group. Functional disability was not improved. No serious or life threatening events were reported. Conclusions Weak evidence was found of an effect of acupuncture on persistent non-specific low back pain at 12 months, but stronger evidence of a small benefit at 24 months. Referral to a qualified traditional acupuncturist for a short course of treatment seems safe and acceptable to patients with low back pain. Trial registration ISRCTN80764175 [controlled-trials.com].