Management of sickle cell priapism with etilefrine

• Published in: Archives of disease in childhood Vol. 85; no. 1; pp. 52 - 53
• Main Authors: Gbadoé, A D, Atakouma, Y, Kusiaku, K, Assimadi, J K
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health 01-07-2001; BMJ; BMJ Publishing Group Ltd; BMJ Publishing Group LTD; BMJ Group
• Subjects: Administration, Oral; Adolescent; Adrenergic alpha-Agonists - administration & dosage; alpha adrenergic agonist; Anemia, Sickle Cell - complications; Anemia, Sickle Cell - drug therapy; Anemias. Hemoglobinopathies; Biological and medical sciences; Care and treatment; Child; Child, Preschool; Children; Diseases; Diseases of red blood cells; Drug therapy; Etilefrine - administration & dosage; Exercise; General and Acute Paediatrics; Hematologic and hematopoietic diseases; Home Management; Hospitals; Humans; Injections; Male; Medical sciences; Patient safety; Patients; Pediatric diseases; Priapism; Priapism - drug therapy; Priapism - etiology; Prospective Studies; Secondary Prevention; sickle cell anaemia; Sickle cell anemia; Sickle cell anemia in children; Time Factors; Treatment Outcome; Tropical medicine; United Kingdom; Human; Hemoglobinopathy; Sickle cell anemia; Erection disorders; Toxicity; Treatment efficiency; Oral administration; Male; Hemopathy; Genetic disease; Priapism; Chemotherapy; Hemolytic anemia; Treatment; Etilefrine; Complication; Intracavernous administration; Male genital diseases; Child
• ISSN: 0003-9888; 1468-2044
• DOI: 10.1136/adc.85.1.52

Intracavernous injections of etilefrine were effective in seven children with acute sickle cell priapism, and stuttering priapism resolved in five children after one to seven months of oral etilefrine. Compared with our previous reports in adults, etilefrine appears to be more effective in childhood.