Monitoring cardiovascular function in infants with chronic lung disease of prematurity

• Published in: Archives of disease in childhood. Fetal and neonatal edition Vol. 87; no. 1; pp. F15 - F18
• Main Author: Abman, S H
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health 01-07-2002; BMJ; BMJ Publishing Group Ltd; BMJ Publishing Group LTD; National Library of Medicine - MEDLINE Abstracts
• Subjects: Administration, Inhalation; Biological and medical sciences; Blood Pressure - physiology; BPD; bronchopulmonary dysplasia; Bronchopulmonary Dysplasia - etiology; Calcium channels; Cardiovascular Diseases - diagnosis; Cardiovascular Diseases - etiology; cardiovascular function; Cardiovascular system; Care and treatment; Chronic Disease; chronic lung disease; CLD; ECG; electrocardiogram; Health risks; Humans; Hypertension; Hypertension, Pulmonary - etiology; Hypertension, Pulmonary - physiopathology; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases - diagnosis; Infant, Premature, Diseases - physiopathology; Infant, Premature, Diseases - therapy; Infants (Premature); inhaled nitric oxide; iNO; left ventricular hypertrophy; Lung diseases; Lung Diseases - complications; Lung Diseases - physiopathology; Lung Diseases - therapy; LVH; Medical sciences; Mortality; Nitric oxide; Nitric Oxide - administration & dosage; Oxygen - blood; Oxygen - therapeutic use; Partial Pressure; Pediatric respiratory diseases; Pneumology; premature; Premature birth; Pulmonary Circulation - physiology; pulmonary hypertension; pulmonary vascular resistance; PVR; RDS; Respiratory distress syndrome; Respiratory system : syndromes and miscellaneous diseases; Respiratory therapy; Symposium; Vascular Resistance - physiology; United States; Human; Lung disease; High risk; Pregnancy disorders; Respiratory disease; Cardiovascular disease; Medical screening; Pulmonary hypertension; Left ventricle; Chronic; Prematurity; Surveillance; Heart disease; Complication; Child; Hypertrophy
• ISSN: 1359-2998; 1468-2052
• DOI: 10.1136/fn.87.1.F15

In addition to persistent airways disease, survivors of premature birth with chronic lung disease are at risk of cardiovascular sequelae, including pulmonary hypertension, systemic hypertension, left ventricular hypertrophy, and exercise intolerance. The major treatment of pulmonary hypertension is supplemental oxygen, but drugs such as calcium channel blockers may also be required. The use of inhaled nitric oxide for its long term management is being investigated