Employing Genetic Markers to Improve Diagnosis of Thyroid Tumor Fine Needle Biopsy

Fine-Needle Aspiration (FNA) is the most widely used and cost-effective preoperative test for the initial evaluation of a thyroid nodule, although it has limited diagnostic accuracy for several types of tumors. Patients will often receive cytological report of indeterminate cytology and are referred...

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Bibliographic Details
Published in:	Current genomics Vol. 12; no. 8; pp. 589 - 596
Main Author:	Cerutti, Janete M
Format:	Journal Article
Language:	English
Published:	United Arab Emirates Bentham Science Publishers Ltd 01-12-2011 Bentham Science Publishers
Subjects:	Benign Biopsy Genetic markers Malignancy Nodules Reviews Surgery Thyroid Tumors follicular thyroid adenoma Follicular thyroid carcinoma indeterminate nodule C1orf24 FNA ITM1 molecular markers
Online Access:	Get full text
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Summary:	Fine-Needle Aspiration (FNA) is the most widely used and cost-effective preoperative test for the initial evaluation of a thyroid nodule, although it has limited diagnostic accuracy for several types of tumors. Patients will often receive cytological report of indeterminate cytology and are referred to surgery for a more accurate diagnosis. An improved test would help physicians rapidly focus treatment on true malignancies and avoid some unnecessary treatment of benign tumors. This review will discuss current molecular markers that may improve thyroid nodule diagnosis.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Article-1 ObjectType-Feature-2
ISSN:	1389-2029 1875-5488
DOI:	10.2174/138920211798120781