Primary hepatic neuroendocrine tumor

• Published in: Endocrinology, diabetes & metabolism case reports Vol. 2021; no. 1; pp. 1 - 7
• Main Authors: Tuan Linh, Le, Minh Duc, Nguyen, Tu Minh, Hoang, Ngoc Cuong, Nguyen, Thu Ha, Vuong, Luan, Dao-Thi, Tra My, Thieu-Thi, Van Lenh, Bui
• Format: Journal Article
• Language: English
• Published: England Bioscientifica Ltd 01-06-2021; Bioscientifica
• Subjects: Adult; Asian - Vietnamese; Endocrine-Related Cancer; Gatroenterology; Liver; Male; Novel Diagnostic Procedure; Oncology; Radiology/Rheumatology; Tumours and Neoplasia; Viet Nam; June; Viet Nam; Liver; Novel diagnostic procedure; Male; Oncology; 2021; Tumours and neoplasia; Radiology/Rheumatology; Adult; Asian - Vietnamese; Endocrine-related cancer; Gatroenterology
• ISSN: 2052-0573; 2052-0573
• DOI: 10.1530/EDM-20-0220

Summary Primary hepatic neuroendocrine tumor (PHNET) is a rare type of neuroendocrine tumor (NET) that is also a primary hepatic tumor. Patients are present with almost no specific clinical symptoms and typically present with negative test results and atypical imaging characteristics; therefore, the differentiation of PHNET from other types of primary hepatic masses can be very difficult. In this article, we describe a case of PHNET that mimicked a liver helminth infection in a 57-year-old man. The diagnosis of PHNET in this patient was challenging, and the final diagnosis was based on imaging, histopathology features, and long-term follow-up. Learning points An uncommon type of neuroendocrine tumor (NET) is a primary hepatic neuroendocrine tumor (PHNET). Primary hepatic neuroendocrine tumors are rare NET lesions found in the liver, characterized by non-specific clinical and imaging results, which can be easily confused with other liver lesions, including HCC and parasitic lesions. To have a conclusive diagnosis and classification, a mixture of many medical assessment techniques, such as imaging, gastrointestinal endoscopy, nuclear medicine, anatomy, including histopathology, and immunohistochemistry, is essential.