Are troponins confusing?

• Published in: Heart (British Cardiac Society) Vol. 89; no. 11; pp. 1285 - 1287
• Main Authors: Collinson, P O, Stubbs, P J
• Format: Journal Article
• Language: English
• Published: England BMJ Publishing Group Ltd and British Cardiovascular Society 01-11-2003; BMJ Publishing Group Ltd; BMJ Publishing Group LTD; Copyright 2003 by Heart
• Subjects: ACC; ACS; Acute coronary syndromes; acute myocardial infarction; American College of Cardiology; AMI; Biomarkers; Biomarkers - blood; Blood clots; cardiac troponin I; cardiac troponin T; Cardiology; Cardiovascular disease; creatine kinase; cTnI; cTnT; ESC; European Society of Cardiology; Gangrene; Heart attacks; Humans; Immunoassay - standards; Laboratories; Methods; Musculoskeletal system; myocardial infarction; Myocardial Infarction - diagnosis; NICI; non-ischaemic cardiac injury; non-ST elevation myocardial infarction; NSTEMI; PICI; primary ischaemic cardiac injury; secondary cardiac ischaemic injury; Sensitivity and Specificity; SICI; Troponin I - blood; Troponin T - blood
• ISSN: 1355-6037; 1468-201X
• DOI: 10.1136/heart.89.11.1285

[...]the use of a rise and fall in the American College of Cardiology/European Society of Cardiology (ACC/ESC) guidelines separates cTnT and cTnI elevations caused by ACS, a primary ischaemic cardiac injury (PICI), from those where there is a sustained injury such as myocarditis. [...]the cardiologist must be aware that different cTnI methods do not always agree and results from bedside testing may not be the same as laboratory testing (and sometimes measure different troponins).