Antimicrobial Activity and Chemical Investigation of Brazilian Drosera

• Published in: Memórias do Instituto Oswaldo Cruz Vol. 99; no. 7; pp. 753 - 755
• Main Authors: Ferreira, Dalva Trevisan, Andrei, César Cornélio, Saridakis, Halha Ostrensky, Faria, Terezinha de Jesus, Vinhato, Elisângela, Carvalho, Kátia Eliane, Daniel, Juliana Feijó Souza, Machado, Sílvio Luiz, Saridakis, Dennis Panayotis, Braz-Filho, Raimundo
• Format: Journal Article
• Language: English
• Published: Brazil Fundação Oswaldo Cruz, Fiocruz 01-11-2004; Instituto Oswaldo Cruz, Ministério da Saúde; Fundação Oswaldo Cruz (FIOCRUZ)
• Subjects: aliphatic compounds; Anti-Bacterial Agents - chemistry; Anti-Bacterial Agents - isolation & purification; Anti-Bacterial Agents - pharmacology; antimicrobial activity; Candida albicans; Candida albicans - drug effects; Drosera; Drosera - chemistry; Drosera species; Drosera species - Droseraceae - antimicrobial activity - plumbagin - aliphatic compounds; Droseraceae; Enterococcus faecium; Escherichia coli; Gram-Negative Bacteria - drug effects; Gram-Positive Bacteria - drug effects; Klebsiella pneumoniae; Microbial Sensitivity Tests; PARASITOLOGY; Plant Extracts - chemistry; Plant Extracts - pharmacology; plumbagin; Pseudomonas aeruginosa; Salmonella choleraesuis; Staphylococcus aureus; TROPICAL MEDICINE; Brazil; Droseraceae; plumbagin; Drosera species; aliphatic compounds; antimicrobial activity
• ISSN: 1678-8060; 0074-0276; 0074-0276; 1678-8060
• DOI: 10.1590/S0074-02762004000700016

The antimicrobial activity of three different extracts (hexanic, ethyl
acetate, methanol) obtained from Brazilian Drosera species (D.
communis, D. montana var. montana, D. brevifolia, D. villosa var.
graomogolensis, D. villosa var. villosa, Drosera sp. 1, and
≥Drosera sp. 2 ) were tested against Staphylococcus aureus (ATCC
25923), Enterococcus faecium (ATCC23212), Pseudomonas aeruginosa
(ATCC27853), Escherichia coli (ATCC11229), Salmonella choleraesuis
(ATCC10708), Klebsiella pneumoniae (ATCC13883), and Candida albicans (a
human isolate). Better antimicrobial activity was observed with D.
communis and D. montana var. montana ethyl acetate extracts.
Phytochemical analyses from D. communis, D. montana var. montana and D.
brevifolia yielded 5-hydroxy-2-methyl-1,4-naphthoquinone (plumbagin);
long chain aliphatic hydrocarbons were isolated from D. communis and
from D. villosa var. villosa, a mixture of long chain aliphatic
alcohols and carboxylic acids, was isolated from D. communis and
3β-O-acetylaleuritolic acid from D. villosa var. villosa.