Low frequency of human papillomavirus detection in prostate tissue from individuals from Northern Brazil

• Published in: Memórias do Instituto Oswaldo Cruz Vol. 104; no. 4; pp. 665 - 667
• Main Authors: Costa, Solange do PSE, Lazéra, Márcia dos S, Santos, Wallace RA, Morales, Bernardina P, Bezerra, Cláudia CF, Nishikawa, Marília M, Barbosa, Gláucia G, Trilles, Luciana, do Nascimento, José LM, Wanke, Bodo
• Format: Journal Article
• Language: English
• Published: Brazil Fundação Oswaldo Cruz, Fiocruz 01-07-2009; Instituto Oswaldo Cruz, Ministério da Saúde; Fundação Oswaldo Cruz (FIOCRUZ)
• Subjects: benign prostate hyperplasia; DNA, Viral - analysis; Genotype; human papillomavirus; human papillomavirus - prostate cancer - benign prostate hyperplasia; Humans; Male; Middle Aged; Neoplasm Staging; Papillomaviridae - genetics; Papillomaviridae - isolation & purification; Papillomavirus Infections - diagnosis; Papillomavirus Infections - virology; PARASITOLOGY; Polymerase Chain Reaction; prostate cancer; Prostatic Hyperplasia - virology; Prostatic Neoplasms - virology; TROPICAL MEDICINE; prostate cancer; human papillomavirus; benign prostate hyperplasia
• ISSN: 1678-8060; 0074-0276; 1678-8060; 0074-0276
• DOI: 10.1590/S0074-02762009000400024

The presence of human papillomavirus (HPV) was evaluated in 65 samples
of prostate tumours and six samples of prostates with benign prostatic
hyperplasia from individuals from Northern Brazil. We used a highly
sensitive test, the Linear Array HPV Genotyping Test, to detect 37 high
and low-risk HPV types. In this study, only 3% of tumour samples showed
HPV infection. Our findings support the conclusion that, despite the
high incidence of HPV infection in the geographic regions studied, HPV
was not associated with a higher risk of prostate cancer. To our
knowledge, this is the first study evaluating the frequency of HPV
detection in prostatic tissue of individuals from Brazil.