Prevalence, Incidence, Risk and Protective Factors of Amnestic Mild Cognitive Impairment in the Elderly in Shanghai

• Published in: Current Alzheimer research Vol. 14; no. 4; p. 460
• Main Authors: Wang, Tao, Xiao, Shifu, Chen, Kewei, Yang, Cece, Dong, Shuhui, Cheng, Yan, Li, Xia, Wang, Jinghua, Zhu, Minjie, Yang, Fuzhong, Li, Guanjun, Su, Ning, Liu, Yuanyuan, Dai, Jing, Zhang, Mingyuan
• Format: Journal Article
• Language: English
• Published: United Arab Emirates 01-04-2017
• Subjects: Age Factors; Aged; China - epidemiology; Cognitive Dysfunction - epidemiology; Female; Humans; Incidence; Male; Middle Aged; Prevalence; Protective Factors; Risk Factors; Risk Reduction Behavior; Sleep; Socioeconomic Factors; prevalence; Amnestic mild cognitive impairment; odds ratio; protective factor; incidence; risk factor
• ISSN: 1875-5828
• DOI: 10.2174/1567205013666161122094208

Amnestic MCI (aMCI) has notably increased in Shanghai, China.
The study was designed to estimate the prevalence and incidence rates of aMCI and to determine the risk and protective factors for aMCI among persons ≥ 60 years-old and ≥ 70 years-old in Shanghai communities, respectively.
We carried out this 1-year longitudinal study to survey a random sample of 1,302 individuals ≥ 60 years-old, to collect baseline and follow-up data about lifestyle through self-reports, and vascular and comorbid conditions from medical records and a physical examination. We also analyzed a subgroup of individuals ≥ 70 years-old.
The prevalence rate of aMCI in persons ≥ 60 years-old was 22.3%, and the incidence rate (per 1,000 person-years) was 96.9. Being female was a risk factor for aMCI; protective factors included smoking, drinking tea, engaging in intellectual work before retirement, social activities and hobbies, regular reading habits, and surfing the internet. The prevalence rate of aMCI in persons ≥ 70 years was 30.3%, and the incidence rate was 145.6. Smoking, drinking tea, and surfing the internet were not protective factors for this age group (≥ 70 years).
The present study indicates that aMCI is a considerable health problem in Shanghai. Preventive strategies for aMCI are needed to enhance lifestyle factors that promote brain activity.