Cohort profile: the Coronary Artery disease Risk Determination In Innsbruck by diaGnostic ANgiography (CARDIIGAN) cohort

• Published in: BMJ open Vol. 8; no. 6; p. e021808
• Main Authors: Wanitschek, Maria, Edlinger, Michael, Dörler, Jakob, Alber, Hannes F
• Format: Journal Article
• Language: English
• Published: England BMJ Publishing Group LTD 01-06-2018; BMJ Publishing Group
• Subjects: Age; Angina pectoris; Biomarkers; Cardiology; Cardiovascular disease; Cardiovascular Medicine; Clinical decision making; Cohort analysis; Coronary vessels; Decision making; Epidemiology; Health risk assessment; Heart surgery; Hospitals; Laboratories; Medical diagnosis; Medical imaging; Medical prognosis; Patients; Security services; Austria; coronary artery disease; elective cardiac catheterisation; cohort study; cardiovascular risk factors; clinical epidemiology
• ISSN: 2044-6055; 2044-6055
• DOI: 10.1136/bmjopen-2018-021808

PurposeThe Coronary Artery disease Risk Determination In Innsbruck by diaGnostic ANgiography (CARDIIGAN) cohort is aimed to gain a better understanding of cardiovascular risk factors and their relation to the diagnosis and severity of coronary artery disease, as well as to the long-term prognosis in consecutive (including revascularised) patients referred for elective coronary angiography.ParticipantsThe included patients visited the University Clinic of Cardiology at Innsbruck (Austria), which fulfils a secondary and tertiary hospital function. Inclusion took place in the period between February 2004 and April 2008 and resulted in a total of 8296 patients aged 18–91 years; 65% of them were men.Findings to dateThere was one follow-up round on vital status through record linkage for 84% of the cohort (those with residence in Tyrol), resulting in a follow-up duration of over 5.5 to nearly 10.0 years among survivors. The data contain basic patient characteristics, cardiovascular risk factors, laboratory measurements, medications, detailed information on the extent and severity of coronary artery disease, revascularisation history, treatment strategy and mortality specifics. A few studies have already been published.Future plansVarious diagnostic and prognostic studies are planned, also concerning complications, competing risks and cost-effectiveness. Collaboration with other research groups is welcomed.