Current Knowledge Regarding Pharmacological Profile and Chemical Constituents of Gynura procumbens

• Published in: Current topics in medicinal chemistry Vol. 21; no. 29; p. 2671
• Main Authors: Haque, Ehfazul, Kamal, Mir Shahriar, Tahsin, Md Rafat, Ahmed, Raju, Choudhury, Jakir Ahmed, Chowdhury, Abu Asad, Kabir, Shaila, Amran, Md Shah, Uddin, Md Sahab
• Format: Journal Article
• Language: English
• Published: United Arab Emirates 01-01-2021
• Subjects: Animals; Asteraceae - chemistry; Humans; Plant Extracts - chemistry; Plant Extracts - pharmacology; Plant Extracts - therapeutic use; Plants, Medicinal - chemistry; Therapeutic agents; Alkaloids; Gynura procumbens; Chemical constituents; Pharmacological activity; Phytochemistry
• ISSN: 1873-4294
• DOI: 10.2174/1568026621666211004094902

Gynura procumbens (Lour.) Merr. is a well-known plant used in folkloric medicine in tropical Asian countries. The plant is prevalently employed by traditional healers in the treatment of diabetes, cancer, hypertension, inflammation, fever, and skin disorders. Several scientific studies reported that Gynura procumbens possesses considerable therapeutic value for the development of emerging treatment options. The diverse pharmacological effects of this plant are attributed to its vast phytoconstituent content. Different chemical classes, including alkaloids, flavonoids, phenolics, steroids, proteins, and polysaccharides, have been isolated from this plant. In this review, we tried to explore the different aspects of Gynura procumbens as an established medicinal plant. The data gathered here give an indication that the plant Gynura procumbens is a good natural source of chemical compounds with different types of pharmacological actions, and these chemical compounds can be used as models for the development of de novo therapeutic agents.