Labeling strategies with F-18 for positron emission tomography imaging

The labeling of probes with fluorine-18 [(18)F, β(+); 96.7%] continues to play a considerably important role in the development of positron emission tomography (PET) as a modality for both clinical research and clinical diagnoses. This review summarizes the strategies and recent developments in the...

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Bibliographic Details
Published in:	Medicinal chemistry (Shp-sariqah, United Arab Emirates) Vol. 7; no. 5; p. 334
Main Authors:	Gu, Yonghong, Huang, Dong, Liu, Zhiguo, Huang, Jiaguo, Zeng, Wenbin
Format:	Journal Article
Language:	English
Published:	Netherlands 01-09-2011
Subjects:	Animals Fluorine Radioisotopes - chemistry Humans Positron-Emission Tomography Radiopharmaceuticals - chemical synthesis Radiopharmaceuticals - chemistry
Online Access:	Get more information
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Summary:	The labeling of probes with fluorine-18 [(18)F, β(+); 96.7%] continues to play a considerably important role in the development of positron emission tomography (PET) as a modality for both clinical research and clinical diagnoses. This review summarizes the strategies and recent developments in the fluorine-18 labeling of probes for PET imaging. Problems and issues relating to the practical production of fluorine-18 currently in widespread use are also discussed.
ISSN:	1875-6638
DOI:	10.2174/157340611796799140