A case of variably protease-sensitive prionopathy treated with doxycyclin

[...]this case fulfilled surveillance criteria for probable sCJD. Following the guidelines of an ongoing therapeutic trial, 2 the patient was treated with 100 mg doxycycline per day. [...]December 2008, she was examined five times (see online supplementary material).

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Bibliographic Details
Published in:	Journal of neurology, neurosurgery and psychiatry Vol. 86; no. 7; pp. 816 - 818
Main Authors:	Assar, Hamid, Topakian, Raffi, Weis, Serge, Rahimi, Jasmin, Trenkler, Johannes, Höftberger, Romana, Aboulenein-Djamshidian, Fahmy, Ströbel, Thomas, Budka, Herbert, Yull, Helen, Head, Mark W, Ironside, James W, Kovacs, Gabor G
Format:	Journal Article
Language:	English
Published:	England BMJ Publishing Group LTD 01-07-2015
Subjects:	Anti-Bacterial Agents - therapeutic use Brain - pathology Creutzfeldt-Jakob disease Diffusion Magnetic Resonance Imaging Doxycycline - therapeutic use Female Humans Middle Aged Neuropathology Prion Diseases - diagnosis Prion Diseases - drug therapy Prion Diseases - pathology Rodents Treatment Outcome NEUROPATHOLOGY PRION CREUTZFELDT-JAKOB DISEASE POST MORTEM HISTOPATHOLOGY
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Description
Summary:	[...]this case fulfilled surveillance criteria for probable sCJD. Following the guidelines of an ongoing therapeutic trial, 2 the patient was treated with 100 mg doxycycline per day. [...]December 2008, she was examined five times (see online supplementary material).
ISSN:	0022-3050 1468-330X
DOI:	10.1136/jnnp-2014-309871