Sex/Gender Differences in Metabolism and Behavior: Influence of Sex Chromosomes and Hormones
The National Institutes of Health (NIH) in the United States has been directing basic and clinical scientists to consider potential sex differences and perform their studies using cells and tissues derived from both males and females and using both male and female subjects since 2014. A better under...
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| Published in: | International Journal of Endocrinology Vol. 2015; pp. 401 - 402-044 |
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| Main Authors: | , , |
| Format: | Journal Article |
| Language: | English |
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Egypt
Hindawi Limiteds
01-01-2015
Hindawi Publishing Corporation John Wiley & Sons, Inc Hindawi Limited |
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| Abstract | The National Institutes of Health (NIH) in the United States has been directing basic and clinical scientists to consider potential sex differences and perform their studies using cells and tissues derived from both males and females and using both male and female subjects since 2014. A better understanding of the mechanisms underlying the sex-based differences in behavior/metabolism and of the influences of sex chromosomes and hormones is expected to lead to novel therapeutic strategies that would benefit patients of both sexes and enhance the concept of individualized medicine. [...]adequate representation of both sexes in the basic and translational preclinical studies should be provided, as emphasized by the NIH recent requirement intended to minimize sex biases in preclinical research. The goal of this special issue is to stimulate the continuing efforts to demonstrate the breadth of the behavioral, physiological, cellular, and molecular processes beyond the reproductive system which exhibit sex-based differences under physiological and pathological conditions, with a particular concentration on sex chromosomes and hormones. |
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| AbstractList | The National Institutes of Health (NIH) in the United States has been directing basic and clinical scientists to consider potential sex differences and perform their studies using cells and tissues derived from both males and females and using both male and female subjects since 2014. A better understanding of the mechanisms underlying the sex-based differences in behavior/metabolism and of the influences of sex chromosomes and hormones is expected to lead to novel therapeutic strategies that would benefit patients of both sexes and enhance the concept of individualized medicine. [...]adequate representation of both sexes in the basic and translational preclinical studies should be provided, as emphasized by the NIH recent requirement intended to minimize sex biases in preclinical research. The goal of this special issue is to stimulate the continuing efforts to demonstrate the breadth of the behavioral, physiological, cellular, and molecular processes beyond the reproductive system which exhibit sex-based differences under physiological and pathological conditions, with a particular concentration on sex chromosomes and hormones. |
| Audience | Academic |
| Author | Hai-Fei Shi Roshanak Rahimian Lynda M. Brown |
| AuthorAffiliation | 1 Department of Biology, Miami University, Oxford, OH 45056, USA 2 Foods and Nutrition Science Program, North Carolina A&T State University, Greensboro, NC 27411, USA 3 Department of Physiology and Pharmacology, Thomas J. Long School of Pharmacy & Health Sciences, University of the Pacific, Stockton, CA 95211, USA |
| AuthorAffiliation_xml | – name: 2 Foods and Nutrition Science Program, North Carolina A&T State University, Greensboro, NC 27411, USA – name: 3 Department of Physiology and Pharmacology, Thomas J. Long School of Pharmacy & Health Sciences, University of the Pacific, Stockton, CA 95211, USA – name: 1 Department of Biology, Miami University, Oxford, OH 45056, USA |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/26491439$$D View this record in MEDLINE/PubMed |
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| Copyright | Copyright © 2015 Haifei Shi et al. COPYRIGHT 2015 John Wiley & Sons, Inc. Copyright © 2015 Haifei Shi et al. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. Copyright © 2015 Haifei Shi et al. 2015 |
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| SubjectTerms | Behavior Endocrinology Females Gender differences Hormones Hormones, Sex Influence Males Mental disorders Metabolic disorders Physiological aspects Physiology Reproductive system Researchers Sex chromosomes Sexes Womens health |
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| Title | Sex/Gender Differences in Metabolism and Behavior: Influence of Sex Chromosomes and Hormones |
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